cell injury
inflammation
blood vessels
giant cell arteritis (h&e)Clinically - 80yoF, haedache, jaw and tongue pain,, problems with vision&coordination, dizziness. Association with polymyalgia rheumatica.
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necrotising vasculitis involving medium and small arteries (GPA), superior mesenteric artery (h&e)Clinically - right-sided abdominal pain due to necrosis of small intestine
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Necrotising & crescentic glomerulonephritis (GPA)Clinically - rapidly progressive glomerulonephritis (subacute rise in creatinine, haematuria, elevated blood pressure)
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