cell injury

MYOCARDIAL INFARCTION - MICRO

BRAIN INFARCTION - GROSS

BRAIN INFARCTION - MICRO

HEPATITIS C - APOPTOSIS

inflammation

blood vessels

giant cell arteritis (h&e)

Clinically - 80yoF, haedache, jaw and tongue pain,, problems with vision&coordination, dizziness. Association with polymyalgia rheumatica.

necrotising vasculitis involving medium and small arteries (GPA), superior mesenteric artery (h&e)

Clinically - right-sided abdominal pain due to necrosis of small intestine

Necrotising & crescentic glomerulonephritis (GPA)

Clinically - rapidly progressive glomerulonephritis (subacute rise in creatinine, haematuria, elevated blood pressure)​

leucocytoclastic vasculitis, skin, Systemic lupus erythematosus (h&e)

Clinically - palpable purpura of extremities

malignant hypertension, incl. hyperplastic arteriolosclerosis

Clinically - abdominal pain; elevated serum creatinine level (4.25mg/dl); microhaematuria; proteinuria of 0.9mg/dl; oliguria (500ml/24h); anaemia; history of continuous elevated diastolic blood pressure (>120 mmHg)

 deep vein thrombosis, branches of femoral vessels (h&e)

Clinically - leg edema, pain &tenderness, pain on dorsiflexion of the foot, rarely cyanosis. 50% of DVT cases lack symptoms & symptoms are not specific

ARTERIO-VENOUS MALFORMATION, ANKLE (h&e)

diabetic nephropathy, incl. hyaline arteriolosclerosis (pas staiN)

Clinically - long history of type 2 diabetes mellitus

amyloidosis of the kidney, (cONGO RED STAIN)

Clinically - 70yoF, massive proteinuria with nephrotic syndrome; paraproteinemia

heart

Acute fibrinous pericarditis

acute rheumatic heart disease

Acute myocardial infarction, Mural thrombus of heart, Pericarditis secondary to acute myocardial infarc

bacterial endocarditis

healing myocardial infarction

cardiac myxoma

HYPERTROPHIC CARDIOMYOPATHY, DILATED PHASE, RIGHT VENTRICLE

Diffuse interstitial myocarditis with amastigote forms of Trypanosoma cruzi

male reproductive

bph

Male 69 years. Catheterised. TURP. Specimen site - Prostate chips. Gross: 51.6 grams of tissue chippings, 16 grams randomly sampled and submitted.

Pca gs 3+4=7

PCA gs 4+4=8

seminoma

embryonal carcinoma + choriocarcinoma

testicular atrophy - cryptorchid testis

Mixed germ cell tumour (embryonal carcinoma, yolk sac tumour, teratoma)

leidig cell tumor

Squamous cell carcinoma in situ (Bowen's disease)

Male 67 years. Biopsy ventral surface of penis. Warty growth - timescale unknown. Macro: Irregular grey skin ellipse 12 x 8 x 4 mm with diffuse surface irregularity.

PAPILLARY UROTHELIAL CARCINOMA, LOW GRADE

NORMAL PROSTATE

METASTATIC ADENOCARCINOMA OF THE PROSTATE

female reproductive

KIDNEY

SKIN